Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Lupus erythematosus
Etiology, pathogenesis
  • multisystem autoimmune disease (systemic LE)
  • variety of autoantibodies, especially against double stranded DNA
  • immune complex formation, which trigger inflammatory reactions
Clinical signs
  • acute (or subacute) forms are serious, involve other organs (esp. kidneys)
  • fatigue, fever
  • chronic cutaneous form (chronic discoid LE, CDE) is limited to the skin: red, slightly raised lesions above the neck; butterfly rash is typical
  • photosensitivity
Pictures

Another chapter on lupus erythematosus with images is available at: