Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
Up
Next
Back
×
+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Lupus erythematodes, acute
Clinical signs
  • acute (and subacute) lupus erythematodes is dangerous (affects other organs, esp. kidneys)
  • skin: face, scalp, fingers
  • photosensitivity
  • maculopapulous exanthema, generalised
  • butterfly exanthema on the cheeks
  • at the same time lesions of CDE, ev. oral ulcerations
  • defluvium, diffuse scarring alopecia
  • vasculitic and hyperkeratotic lesions of the fingers, Raynaud's phenomenon
  • purpura, urticaria, panniculitis, ulcerations, pigment disorders etc.

Lupus erythematodes (992)

Lupus erythematodes (680)

Pictures

SLE, butterfly exanthema: Systemic lupus erythematodes acute, Clinical picture (925)

Acute SLE, butterfly exanthema: Systemic lupus erythematodes, Clinical picture (995)

SLE, butterfly exanthema, discoid: Discoid lupus erythematodes chronic, Clinical picture (993)

Histology

Vacuolar degeneration of the basal cell layer; perivascular and periadnexal lymphocytic infiltration. The infiltration in the acute erythematodes are usually present neutrohils as well. Fibrosis; occasionally vasculitis.

Immunofluorescence: deposits of all kinds of immune complexes and c3 along the dermo-epidermal junction (also in clinically uninvolved skin); rarely anti-Ro and anti-La antibodies among the cells of the basal layer (subacute LE, SLE, Sjögren's syndrome).

Lupus erythematodes (3654)

Lupus erythematodes (3654)

Pictures

SLE, acute: Systemic lupus erythematodes acute, HE 40x (2288) Systemic lupus erythematodes acute, HE 40x (2286) Systemic lupus erythematodes acute, HE 100x (2285)

Another case: Systemic lupus erythematodes acute, HE 40x (2290)

Another case: Systemic lupus erythematodes acute, HE 100x (2289)

Another case: Systemic lupus erythematodes acute, HE 20x (1376)

Another case: Systemic lupus erythematodes acute, HE 20x (4747)

Acute discoid lupus erythematodes: Discoid lupus erythematodes fresh, HE 20x (4748)

Another case: Acute lupus erythematodes, HE 60x (6209) Acute lupus erythematodes, alcian blue 60x (6208)

SLE: Systemic lupus erythematodes, HE 40x (5450)