Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Lupus erythematodes, chronic
Clinical signs
  • insolated areas: face, ears, scalp, neckline
  • red, targetoid lesions if fresh
  • firmly adhering squames
  • follicular hyperkeratosis
  • heals with depigmented scars
  • reactive hyperpigmentations on the periphery
Pictures

Confluent targetoid lesions of the discoid erythematodes, face: Discoid lupus erythematodes chronic, Clinical picture (680)

Fresh lesion, upper lip: Discoid lupus erythematodes chronic, Clinical picture (681)

Chronic cutaneous lupus erythematodes (CDE), butterfly distribution: Discoid lupus erythematodes chronic, Clinical picture (991)

Chronic cutaneous lupus erythematodes (CDE): Discoid lupus erythematodes chronic, Clinical picture (992)

Chronic cutaneous lupus erythematodes (CDE), fresh lesion of the ear: Discoid lupus erythematodes chronic, Clinical picture (994)

Lupus erythematodes, face: Lupus erythematodes, face, Clinical picture (1966)

Chronic discoid lupus erythematodes: Discoid lupus erythematodes chronic, Clinical picture (5737) Discoid lupus erythematodes chronic, Clinical picture (5738) Discoid lupus erythematodes chronic, Clinical picture (5739) Discoid lupus erythematodes chronic, Clinical picture (5740) Discoid lupus erythematodes chronic, Clinical picture (5741) Discoid lupus erythematodes chronic, Clinical picture (5742)

Chronic lupus erythematosus: Systemic lupus erythematodes, Clinical picture (5743) Systemic lupus erythematodes, Clinical picture (5744) Systemic lupus erythematodes, Clinical picture (5745) Systemic lupus erythematodes, Clinical picture (5746) Systemic lupus erythematodes, Clinical picture (5747) Systemic lupus erythematodes, Clinical picture (5748) Systemic lupus erythematodes, Clinical picture (5749) Systemic lupus erythematodes, Clinical picture (5750)

Chronic lupus erythematosus: Discoid lupus erythematodes chronic, Clinical picture (6349)

Histology

Vacuolar degeneration of the basal layer; perivascular and periadnexal lymphocytic infiltrate; fibrosis; sometimes vasculitis. Follicular plugging, atrophy and/or dysmaturation of the epidermis, thickenning of the basement membrane, lymphocytic periadnexal and perivascular infiltrate.

Immunofluorescence: deposits of various kinds of immunocomplexes and C3 along dermo-epidermal junction (the deposits are present in clinically uninvolved skin as well). Direct immunofluorescence sometimes show anti-Ro and anti-La antibodies between the cells of the basal layer (SLE, subacute LE, Sjögren's syndrome).

Direct immunofluorescence sometimes show anti-Ro and anti-La antibodies between the cells of the basal layer (SLE, subacute LE, Sjögren's syndrome).

Pictures

Lupus erythematodes, chronic: Chronic lupus erythematosus of the skin, HE 10x (197)

Lupus erythematodes, chronic: Discoid lupus erythematodes chronic, HE 60x (14040) Discoid lupus erythematodes chronic, PAS 60x (14041)

Lupus erythematodes, chronic: Discoid lupus erythematodes chronic, HE 60x (14038) Discoid lupus erythematodes chronic, PAS 60x (14039)

Another case: Discoid lupus erythematodes chronic, HE 100x (2523)

Lesion of CDE form the face after long lasting corticosteroid treatment: Chronic lupus erythematosus with epidermal atrophy, HE 40x (196)

Another case: Chronic lupus erythemathosus of the skin, HE 20x (194) Chronic lupus erythemathosus of the skin, HE 40x (195)

Another case: Chronic lupus erythematodes of the skin, HE 5x (192) Chronic lupus erythematodes of the skin, HE 20x (190) Chronic lupus erythematodes of the skin, HE 40x (191)

Another case: Discoid lupus erythematodes chronic, HE 40x (6137)

Another case: Chronic erythematodes of the skin, HE 40x (193)

Another case: Discoid lupus erythematodes chronic, HE 40x (2706)

Another case: Discoid lupus erythematodes chronic, HE 20x (5354)

Another case: Lupus erythematosus, HE 60x (10752)

Another case: Lupus erythematosus, HE 60x (10753)

Lupus erythematodes: Discoid lupus erythematodes chronic, HE 60x (12083)

Lupus erythematodes: Discoid lupus erythematodes chronic, HE 60x (12084)

Lupus erythematodes: Lupus erythematodes, HE 60x (12018)

Lupus erythematodes: Lupus erythematodes, HE 60x (12019)

Lupus erythematodes: Discoid lupus erythematodes chronic, HE 60x (12085)

Lupus erythematodes: Lupus erythematodes, HE 40x (12619)

Lupus erythematodes: Lupus erythematodes, HE 40x (12826)

Lupus erythematodes: Systemic lupus erythematodes, HE 60x (13193) Systemic lupus erythematodes, HE 40x (12907)

Another case, with dense lymphocytic infiltrates: Discoid lupus erythematodes chronic, HE 40x (3654)

Another case: Lupus erythematodes, discoid, HE 60x (10996)

Direct fluorescence in chronic lupus erythematosus (anti-IgM, FITC): Chronic lupus erythematodes of the skin, anti-IgM, FITC, Evans 20x (470) Chronic lupus erythematodes of the skin, anti-IgM, FITC, Evans 40x (471) Chronic lupus erythematodes of the skin, anti-fibrin, FITC, Evans 10x (535) Chronic discoid lupus erythematodes, anti-IgM, FITC, Evans 20x (488) Chronic discoid lupus erythematodes, anti-IgM, FITC, Evans 40x (489) Lupus erythematodes, anti-IgG, FITC 20x (570) Lupus erythematodes, anti-IgG, FITC 40x (571)

Discoidní lupus erythematodes chronický, milia (ucho): Discoid lupus erythematodes chronic, milia (ear), HE 40x (5505)

Alopecia, CDE Chronic lupus erythematodes, alopecia, HE 10x (490) Chronic lupus erythematodes, alopecia, HE 10x (491) Chronic lupus erythematodes, alopecia, HE 40x (492)