Pathology
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Atlas of Bone Marrow pathology
Mojmir Moulis, Josef Feit et al.
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+ Introduction
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+ Bone Marrow Pathology
Refractory Cytopenia with Multilineage Dysplasia (RCMD)
Clinical signs
  • dysplastic changes are present in more than 10% of cells from two or more lineages
  • prognosis: about 11% of patients develop AML, median survival time is approx. 33 months
  • there are fewer than 5% of myeloblasts in the bone marrow
  • bicytopenia or pancytopenia
  • the number of ringed sideroblasts may be increased (RCMD-RS)