Pathology
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Atlas of Bone Marrow pathology
Mojmir Moulis, Josef Feit et al.
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+ Bone Marrow Pathology
Plasma Cell Neoplasms
Introduction

Immunosecretive tumorous disorders caused by expansion of a particular clone of differentiated B cells, which produce a single type of immunoglobulin. Previously called plasma cell dyscrasias.

Classification
  • plasma cell (multiple) myeloma (MM)
  • solitary plasmacytomas: localized tumors which arise in bones or soft tissues. They contain cells morphologically identical to the cells of plasma cell myeloma. This myeloma develops in about 55% of cases of solitary plasmocytoma.
  • monoclonal gammapathy of undetermined significance (MGUS)