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Atlas of Bone Marrow pathology
Mojmir Moulis, Josef Feit et al.
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Mastocytosis
Introduction

Clonal neoplastic mast cell proliferation. Mast cells accummulate in one or more organs. Mastocytosis is characterized by multifocal cohesive aggregates or infiltrates formed by abnormal mast cells.

Classification
  • Cutaneous mastocytosis (CM)
  • Indolent systemic mastocytosis (ISM)
  • Systemic mastocytosis with associated clonal haematological non-mast cell lineage diseases (SM-AHNMD)
  • Aggressive systemic mastocytosis (ASM)
  • Mast cell leukemia (MCL)
  • Mast cell sarcoma (MCS)
  • Extracutaneous mastocytoma