Pathology
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Atlas of Bone Marrow pathology
Mojmir Moulis, Josef Feit et al.
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+ Bone Marrow Pathology
Anemias
Introduction

Anemia is an abnormally low number of circulating erythrocytes leading to low hemoglobin levels in peripheral blood (less than 130 g/l in men or 120 g/l in women).

The classification of anemias is complex and since it is a part of hematology, this text will focus on basic types of anemias and the morphological changes they cause in the bone marrow.

Clinical signs
  • fatigue
  • dyspnea
  • tachycardia with palpitations
  • pale skin
  • neurologic symptoms (dizziness, faintness, headache)
  • other
Classification
  • Anemia resulting from an increased peripheral blood loss
    • acute posthemorrhagic anemia
    • chronic posthemorrhagic anemia
  • Anemia resulting from a decreased erythrocyte production
    • megaloblastic anemia
    • sideropenic anemia
    • myelodysplastic syndrome
    • aplastic anamia
    • anemia caused by hematopoietic depression
    • chronic kidney disease anemia
    • anemias of chronic disorders
  • Anemia resulting from an increased erythrocyte destruction
    • hemolytic anemia