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Atlas of Bone Marrow pathology
Mojmir Moulis, Josef Feit et al.
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Amegakaryocytic thrombocytopenia
Introduction

Amegakaryocytic thrombocytopenia is either congenital or acquired (amegakaryocytic thrombocytopenic purpura).

Introduction

Autoimmune diseases, drugs, toxins, hepatic cirrhosis, lymphoproliferative disorders and other malignacies.

Histology

Bone marrow is normocellular, erythropoiesis and myelopoiesis are normal. Megakaryocytes are substantially decreased in number or sometimes even completely missing.