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Atlas of Bone Marrow pathology
Mojmir Moulis, Josef Feit et al.
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Sideropenic Anemia
Introduction

Anemia caused by inadeqaute iron deposits resulting from insufficient iron intake or increased loss (repeated or prolonged bleeding).

Clinical signs

Microcytic hypochromic anemia.

Histology
  • Peripheral blood: hypochromic microcytic anemia, anisocytosis, polychromasia is absent, poikilocytosis.
  • Bone marrow: normocellular or slightly hypercellular with increased normoblastic erythropoiesis. More mature normoblasts contain light cytoplasm with decreased hemoglobin levels. Stainable stromal iron is missing.