Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Granulomatosis disciformis Miescher
Classification

Now considered to be a variant of necrobiosis lipoidica.

Clinical signs
  • disc-shaped plaques
  • locations: pretibial regions
  • no asscociation with diabetes
Histology

Large granulomas with macrophages (often large, multinuclear) and lymphocytes. Necrobiosis is usually minimal.