Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Erythema dyschromicum perstans
Introduction

Chronic condition, where destruction of the basal layer leads to release of pigment into the upper dermis. If active, process is characterized by superficial chronic lymphocytic infiltrate and basal layer vacuolization. Later only melanophages in the upper dermis remain. The process is not specific, pigment incontinence can be seen in many other processes (eg. lichen ruber, fixed druh reaction).

Clinical signs
  • irregular pigmented macules, sometimes in oblique lines
  • pigmented patches
  • slow progress
  • greyish color (“ashy dermatosis”)
  • discoloration persists
  • trunk, arms, face
  • lasts years
Pictures

Erythema dyschromicum perstans: Erythema dyschromicum perstans, Clinical picture (2863) Erythema dyschromicum perstans, Clinical picture (2864) Erythema dyschromicum perstans, Clinical picture (2865)

Another case, child: Erythema dyschromicum perstans, Clinical picture (4010) Erythema dyschromicum perstans, Clinical picture (4011) Erythema dyschromicum perstans, Clinical picture (4013)

Histology

vacuolar degeneration of the basal layer, superficial lymphocytic infiltrate; later scattered melanopgages in the upper dermis.

Etiology, pathogenesis
  • unknown
Pictures

Erythema dyschromicum perstans: Erythema dyschromicum perstans, late, HE 20x (217) Erythema dyschromicum perstans, late, HE 40x (218)

Another case: Erythema dyschromicum perstans, HE 10x (549) Erythema dyschromicum perstans, HE 40x (550) Erythema dyschromicum perstans, Fontana Masson 40x (551)

Another case: Erythema dyschromicum perstans (late), HE 100x (2351) Erythema dyschromicum perstans (late), Fontana Masson 100x (2352)

Another case (clinical picture is here): Erythema dyschromicum perstans, Fontana Masson 40x (3996)

Postinflammatory pigmentation of the papillary corium: Hyperpigmentation postinflammatory, HE 60x (10716)