Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Poikiloderma Rothmund Thomson
Clinical signs
  • rare, autosomal recessive genodermatosis
  • poikiloderma (skin atrophy, irregular pigment distribution and hypopigmentation, vascular dilatation)
  • sometimes increased incidence of malignancies
  • extracutaneous signs:
    • nail dystrophy
    • dystrophic teeth
    • cataracta
    • hypogonadism
    • bone defects
Histology

Skin atrophy, pigment incontinence, basal layer keratinocytes are apoptotic.

Pictures