Fetopathology and developmental pathology of the embryo and fetus: Pseudohermaphroditism femininus

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+ Atlas of fetal pathology

+ Congenital malformations

+ Physiological developement of an embryo and fetus, growth and changes of the external shape

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+ Congenital malformations of genital system and somatosexual congenital disorders

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+ Pseudohermaphroditism masculinus

+ Androgen insensitivity syndrome, testicular feminization syndrome, female XY

+ Pseudohermaphroditism femininus

+ Congenital adrenal hyperplasia

+ Somatosexual disorders with pathologic karyotype

+ Congenital malformations of female genitalia

+ Congenital malformations of the internal genitalia

+ Congenital malformations associated with congenital malformations of urinary system

+ Congenital malformations of the vulva

+ Congenital malformations of the male genital organs

+ Cryptorchidism

+ Congenital malformations of penis and scrotum

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+ Terminal transverse limb defects

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+ Constriction (amniotic) band syndrome

+ Placental inflammation

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Pseudohermaphroditism femininus

Clinical signs

46 XX, ovaria
external: ambiguous genitalia or developing in the male way (virilization):
- in a mild form only clitoris hypertrophy
- in a serious form the newborn girls can be confused with a cryptorchid boy

Etiology

Increased level of androgens during intrauterine development.

Pictures

Masculinization of female fetus caused by continued use of oral contraception till the week 20 of gestation. Progestins included in contraceptives are responsible for the masculinization effect (pseudohermaphroditism): External genital malformation, Macro, autopsy (73310)