Invasive mola (mole proliferans, mole destruens)
Complete or partial mole characterized by aggresive tumor — like behaviour.
In spite of this behaviour invasive mole is not a neoplasm.
- chorionic villi are found within myometrium or vascular spaces
- molar villi may embolize to the lung, vagina or brain (so called
metastatic mole); these emboli are not real metastases because
they undergo regression and do not form a secondary focus
- hCG titres are high
- therapy: invasive mole is managed by chemotherapy
The diagnosis of invasive mole can be confirmed only when
surgical resection is examined. Surgery is not a standard
procedure. That is why treatment is usually applied without
definitive pathologic confirmation.