Pictures
Vulval intraepithelial neoplasia, grade 3:
Vulval intraepithelial neoplasia, grade 3, HE 20x (73379)
Pictures
Endometriosis of the Fallopian tube:
Endometriosis of the Fallopian tube, HE 20x (70736)Endometriosis of the Fallopian tube, HE 40x (70656)
Pictures
Leydig cell tumor:
Leydig cell tumor, HE 40x (70991)Leydig cell tumor, HE 40x (70992)
Dysgerminoma:
Seminoma, HE 40x (70993)
Cystadenoma serosum ovarii:
Cystadenoma serosum ovarii, HE 40x (71008)
Cystadenoma mucinosum ovarii:
Cystadenoma mucinosum ovarii, HE 20x (71009)Cystadenoma mucinosum ovarii, HE 40x (71010)Cystadenoma mucinosum ovarii, HE 40x (71011)Cystadenoma mucinosum ovarii, HE 40x (71012)Mucinous cystadenocarcinoma, borderline, ovary, HE 20x (73397)
Serous papillocarcinoma, invasive, ovary:
Serous papillocarcinoma, invasive, ovary, HE 20x (73413)
Teratoma of the ovary, mature:
Teratoma of the ovary, mature, HE 10x (71013)Teratoma, mature (ovary), HE 40x (70259)Teratoma of the ovary, mature, HE 40x (71014)Teratoma of the ovary, mature, HE 40x (71015)Teratoma of the ovary, mature, HE 40x (71016)Mature teratoma, HE 40x (6410)
Granulosa cell tumor:
Granulosa cell tumor, HE 40x (71017)
Graviditas tubaria:
Graviditas tubaria, HE 20x (71018)
Oophoritis:
Acute oophoritis, HE 20x (73406)
Stromal hyperplasia, ovary:
Stromal hyperplasia, ovary, HE 20x (73416)
Introduction:
Primary ovarian lymphoma (POL) refers to involvement of the ovary with lymphoma but without involvement of any other site. It is an extremely rare yet well recognized situation. It can accounts for 1.5% of ovarian tumours.
The rarity of this condition is probably contributed by lack of lymphoid tissue in the ovary. In almost all of cases instances it tends to comprise of non-Hodgkin lymphoma 0.5% of NHL tends to involve the ovary with diffuse large B-cell lymphoma (DLBCL) being a dominant histological type. Burkitt lymphoma has also been infrequently described.
Radiographic features: CT Once the diagnosis is made CT is the preferred imaging modality of ongoing assessment particularly for staging purposes. Often tends to be hypo-attenuating on CT with mild enhancement post contrast. Ultrasound imaging features are usually non specific. MRI tends to be of relatively homogenous signal.
Staging: this is one of the rare situations where the FIGO staging system isn't used; the standard non-Hodgkin lymphoma staging system is used instead.
History:
Insignificant.
Laboratory values:
Therapy:
Histology:
Diffuse infiltrate of large lymphoid cells, CD20+, CD79a+, CD3-, CD5-, MUM1+, cytoplasmic bcl2+, nuclear bcl6+, cyclin D1-, Ki67 positive in almost 100% of nuclei.
Pictures
Diffuse infiltrate of large lymphoid cells:
Primary diffuse large B cell lymphoma of the ovary, HE 20x (74525)Primary diffuse large B cell lymphoma of the ovary, HE 20x (74526)Primary diffuse large B cell lymphoma of the ovary, HE 20x (74527)Primary diffuse large B cell lymphoma of the ovary, HE 20x (74528)
CD20 positive:
Primary diffuse large B cell lymphoma of the ovary, CD20 20x (74529)
CD79a positive:
Primary diffuse large B cell lymphoma of the ovary, CD79a 20x (74530)
CD3 negative:
Primary diffuse large B cell lymphoma of the ovary, CD3 20x (74531)
CD5 negative:
Primary diffuse large B cell lymphoma of the ovary, CD5 20x (74532)
MUM1 positive:
Primary diffuse large B cell lymphoma of the ovary, MUM1 20x (74519)
CD10 negative:
Primary diffuse large B cell lymphoma of the ovary, CD10 20x (74520)
Cytoplasmic bcl2 positive:
Primary diffuse large B cell lymphoma of the ovary, bcl2 20x (74521)
Nuclear bcl6 positive:
Primary diffuse large B cell lymphoma of the ovary, bcl6 20x (74522)
Cyclin D1 negative:
Primary diffuse large B cell lymphoma of the ovary, Cyklin D1 20x (74523)
Ki67 intranuclear positivity in almost 100% of cells:
Primary diffuse large B cell lymphoma of the ovary, Ki67 20x (74524)
Conclusion:
Pictures
Endometrium (graviditas tubaria):
Endometrium (graviditas tubaria), HE 40x (71203)Endometrium (graviditas tubaria), HE 40x (71204)
Arias-Stella phenomena, extrauterine gravidity:
AS phenomena, extrauterine gravidity, HE 40x (72895)
Molla hydatidosa completa:
Mola hydatidosa, HE 40x (71019)Mola hydatidosa, HE 40x (71020)Mola hydatidosa, HE 40x (71021)
Residua post abortum, products of conception:
Residua post abortum, products of conception, HE 20x (72026) [zoomify]
Graviditas paratubaria:
Graviditas paratubaria, HE 20x (72786)
Pictures
Abortion:
Abortion, Macro, autopsy (71312)
Hyperplasia of the adrenals, pregnancy:
Hyperplasia of the adrenals, pregnancy, Macro, autopsy (71313)
Eclampsia, brain hemorrhage:
Eclampsia, brain hemorrhage, Macro, autopsy (71314)
Choriocarcinoma, metastases to the brain:
Choriocarcinoma, metastases to the brain, Macro, autopsy (71315)
Embryo, 21st day:
Embryo, 21st day, HE 10x (71316)
Mola hydatidosa:
Mola hydatidosa, Macro, autopsy (71317)Mola hydatidosa, Macro, autopsy (71318)
Intrauterine device:
Intrauterine device, Macro, autopsy (71319)
Ovarian agenesis, Turner's syndrome:
Ovarian agenesis, Turner's syndrome, Macro, autopsy (71320)
Serous cystadenocarcinoma, ovaries:
Serous cystadenocarcinoma, ovaries, Macro, autopsy (71321)
Dermoid cysts of the ovary:
Dermoid cyst of the ovaries, Macro, autopsy (71322)
Follicular cyst, ovary:
Follicular cyst, ovary, Macro, autopsy (71323)
Cystadenoma mucinosum, ovary:
Cystadenoma mucinosum, ovary, Macro, autopsy (71324)
Granulosa cell tumor:
Granulosa cell tumor, Macro, autopsy (71325)
Metastasis of a GIT adenocarcinoma to the ovary:
Metastasis of a GIT adenocarcinoma to the ovary, Macro, autopsy (71326)
Metastases of the melanoma, ovary:
Metastases of the melanoma, ovary, Macro, autopsy (71327)
Ovary during the pregnancy:
Ovary during the pregnancy, Macro, autopsy (71328)
Serous cyst of the ovary:
Serous cyst of the ovary, Macro, autopsy (71329)
Uterus and ovary with corpus luteum:
Uterus and ovary with corpus luteum, Macro, autopsy (71330)
Infarctions of the placenta:
Infarctions of the placenta, Macro, autopsy (71331)Infarctions of the placenta, Macro, autopsy (71332)
Placenta, Potter's syndrome:
Placenta, Potter's syndrome, Macro, autopsy (71333)
Normal pregnancy:
Normal pregnancy, Macro, autopsy (71334)
Abortion, abdominal pregnancy:
Abortion, Macro, autopsy (71335)
Pregnancy:
Pregnancy, Macro, autopsy (71339)Pregnancy, Macro, autopsy (71340)Pregnancy, Macro, autopsy (71341)
Choriocarcinoma of the uterus:
Choriocarcinoma of the uterus, Macro, autopsy (71342)
Uterus and plancenta, normal:
Uterus and plancenta, normal, Macro, autopsy (71347)
Uterus after caesarean section:
Uterus after caesarean section, Macro, autopsy (71348)
Uterus after pregnancy:
Uterus after pregnancy, Macro, autopsy (71349)
Uterus, retained placental fragment:
Uterus, retained placental fragment, Macro, autopsy (71350)
Pictures
Retroperitoneal abscess, 19th day after delivery, CT native:
Retroperitoneal abscess, 19th day after delivery, CT native, X-ray (71781)Retroperitoneal abscess, 19th day after delivery, CT contrast, uterus, X-ray (71784)Retroperitoneal abscess, 19th day after delivery, CT contrast, abscess, X-ray (71783)Retroperitoneal abscess, 19th day after delivery, CT contrast, spleen, X-ray (71782)