Contents
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
Login
Logout
 

Disorders of the sweat glands

5  Non-tumorous skin diseases

5.17  Disorders of the sweat glands

Introduction:

Processes listed bellow affect sweat glands, but in addition inflammatory infiltrates of and around sweat glands are present in other diseases (lichen striatus, scleroderma).

5.17.1  Hidradenitis axillaris (suppurativa)

Introduction:

Affects axillary sweat glands. Deep, painful nodules formed by purulent inflammation (usually folliculitis). Heals by scarring. Recurrences are common.

Similar disease, sometimes considered synonymic: acne inversa.

Histology:

Foci of dense neutrophilic infiltrate deep within the dermis, near the sweat glands.

Pictures

Hidradenitis axillaris:
Hidradenitis axillaris, HE 40x (3491)

Hidradenitis axillaris and chromhidrosis:
Hidradenitis axillaris, chromhidrosis, HE 60x (13888)

Further examples of hidradenitis suppurativa:

5.17.2  Eccrine hidradenitis with neutrophils

Clinical signs:

  • location: soles
  • painful nodules

Histology:

Eccrine glands are surrounded by many neutrophils, some glands are necrotic.

5.17.3  Eccrine hidradenitis with neutrophils after chemotherapy

Etiology:

  • occurs after chemotherapy for acute myeloic leukemia
  • rarely in some other diseases or even in healthy patiernts
  • cause is unknown

Clinical signs:

  • erythematous nodules and plaques
  • solitary or multiple
  • affectus usually the trunk and extremities
  • sometimes painful

Histology:

Eccrine (and sometimes apocrine) glands are surrounded by many neutrophils, some glands are necrotic.

5.17.4  Miliaria

Clinical signs:

  • occures after sweating
  • affects especially children in summer

Histology:

Spongiosis and slight lymphocytic infiltrate in the ostia of eccrine sweat glands (milliaria crystallina) or deeper (milliaria rubra).

Pictures

Miliaria rubra:
Miliaria rubra, HE 40x (4141)

5.17.5  Necroses of eccrine sweat glands

Clinical signs:

  • follow comma and some intoxications

Histology:

Glands are necrotic, later with some inflammatory reaction.

5.17.6  Myoclonic epilepsy

Histology:

Dilated eccrine glands may contain homogenous, eosinophilic material (Lafora bodies).

5.17.7  Clear cell metaplasia of eccrine ducts

Histology:

Pale or clear, glycogen containing cells in eccrine ducts.

5.17.8  Syringomucinous metaplasia

Clinical signs:

  • location: usually the soles

Histology:

Eccrine glands with mucin producing cells.

5.17.9  Mucinous metaplasia

Clinical signs:

  • location: variable (but not the soles)

Histology:

Mucin producing cells within the ostia of apocrine sweat glands.

5.17.10  Sweat gland hyperplasia

Introduction:

Enlarged number of sweat glands, dilated ducts in a patient with epidermolysis bullosa dystrophica.

Pictures

Sweat gland hyperplasia:
Hyperplasia of sweat glands, EBD, HE 40x (5519)


Top of this page


If you have problems running this atlas (eg. the windows with images do not open), you might have been referenced directly inside the atlas from some other web site. Thus you might have skipped some entry detection routines. Please try entering through the main web page of this atlas at: www.muni.cz/atlases