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ExpSys: non-tumors
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Metabolic and nutrition problems

5  Non-tumorous skin diseases

5.19  Metabolic and nutrition problems

5.19.1  Pellagra

Etiology:

Deficiency of niacin.

Clinical signs:

  • alcoholics, anorectic patients, patients treated with isoniazid
  • complex of changes (dermatitis, diarrhea, dementia)
  • location: sun exposed areas
  • erythema, sometimes vesicles; later scaling, epidermal atrophy

Histology:

Upper layers of the epidermis are pale; parakeratosis; variable acanthosis; variable superficial lymphohistiocytic infiltrate; dermal fibrosis.

5.19.2  Rachitis, avitaminosis D

Pictures

Rachitis:
Rachitis, CLINIC (5864)

5.19.3  Scorbut, avitaminosis C

Clinical signs:

  • dermal hemorrhages

Pictures

Scorbut:
Scorbut, CLINIC (5946)


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