Therapy based on LCH III. was administered (12 months), with good clinical and radiological response (NAD). Therapy was well tolerated, EFS 18 months on last check-up.
Dense infiltrate of histiocytes with many Touton cells, which was CD68 positive and S100 as well as CD1a negative.
The case was closed as disseminated juvenile xanthogranuloma (xanthoma disseminatum).
Disseminated juvenile xanthogranuloma/xanthoma disseminatum:
Disseminated xanthoma, HE 60x (73927)
Disseminated xanthoma, HE 60x (73926)
Juvenile xanthogranuloma after ALL therapy, S100 40x (73934)
Juvenile xanthogranuloma after ALL therapy, Ki67 40x (73933)
Top of this page