Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Pyoderma gangrenosum
Etiology
  • in about a half of patients associated with other disease (colitis ulcerosa, rheumatoid arthritis, hepatitis)
Clinical signs
  • affects usually lower extremities
  • inflammatory pustule or bulla, early ulcerating
  • ulcerations wiht undermined, inflammed borders, sometimes vegetations
  • no response to therapy
  • sometimes painful
  • heals with cribriform scar
Pictures

Pyoderma gangrenosum: Pyoderma gangrenosum, Clinical picture (902)

Pyoderma gangrenosum, cribriform scars: Pyoderma gangrenosum, Clinical picture (903)

Case of a widespread pyoderma gangrenosum in a patient with ulcerous colitis; gradual improvement: Pyoderma gangrenosum, patient with ulcerous colitis, Clinical picture (4163) Pyoderma gangrenosum, patient with ulcerous colitis, Clinical picture (4164) Pyoderma gangrenosum, patient with ulcerous colitis, Clinical picture (4165) Pyoderma gangrenosum, patient with ulcerous colitis, Clinical picture (4166) Pyoderma gangrenosum, patient with ulcerous colitis, Clinical picture (4167) Pyoderma gangrenosum, patient with ulcerous colitis, Clinical picture (4168)

Histology

Deep and dense infiltrate with many neutrophils, abscess, blood vessels with fibrin deposits, ulcerations.

Pictures

Pyoderma gangrenosum: Pyoderma gangrenosum, HE 20x (602) Pyoderma gangrenosum, HE 40x (603)

Pyoderma gangrenosum in a case of ulcerous colitis (biopsy of the case above), with prominent neutrophilic infiltrate around remnants of a follicle: Pyoderma gangrenosum, HE 40x (4153)

Pyoderma gangrenosum, patient with Crohn's disease: Pyoderma gangrenosum, Crohn's disease, HE 40x (5495)

Another case of pyoderma gangrenosum: Pyoderma gangrenosum, HE 20x (4591)

Another case of pyoderma gangrenosum: Pyoderma gangrenosum, HE 40x (6299)

Another case of pyoderma gangrenosum: Pyoderma gangrenosum, HE 40x (6298) Pyoderma gangrenosum, HE 40x (6296) Pyoderma gangrenosum, HE 40x (6297)