Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Porokeratosis
Introduction

Group of keratinization disorders.

Etiology, pathogenesis
  • autosomal dominant mode of transmision
  • several types
Clinical signs
  • onset at any age, more often in men, chronic course
  • the extremities, trunk, face
  • slightly atrophic lesion with hyperkeratotic border
  • patches with irregular borders, several cm in diameter (Mibelli type)
  • disseminated small lesions, sometimes linear
  • increased risk of the squamous cell carcinoma
Pictures

Actinic porokeratosis: Porokeratosis actinica, Clinical picture (3266) Porokeratosis actinica, Clinical picture (3267) Porokeratosis actinica, Clinical picture (3268) Porokeratosis, Macro (3929) Porokeratosis, Macro (3990)

Histology

Typical is “cornoid lamella”, narrow ridge of hyperkeratosis with parakeratosis. In typical cases we can see two cornoid lamellae leaned one against another. The epidermis in between is often thinned, sometimes dyskeratotic.

Pictures

Porokeratosis: Porokeratosis, HE 40x (5498)

(Porokeratosis linearis): Porokeratosis linearis, HE 10x (65) Porokeratosis linearis, cornoid lamella, HE 40x (66)

Porokeratosis: Porokeratosis, HE 2.5x (1610) Porokeratosis, HE 10x (1609) Porokeratosis, HE 10x (1608)

Actinic disseminated porokeratosis: Porokeratosis, actinic disseminated, HE 20x (2027)

Actinic disseminated porokeratosis: Porokeratosis, actinic disseminated, HE 2.5x (1612) Porokeratosis, actinic disseminated, HE 20x (1611)

Actinic disseminated porokeratosis, another case: Porokeratosis, actinic disseminated, HE 10x (1616)

Porokeratosis: Porokeratosis, HE 10x (1821) Porokeratosis linearis, HE 20x (1615)

Porokeratosis: Porokeratosis, HE 20x (1613)

Another case, thick cornified layer: Porokeratosis, HE 40x (4093)

Porokeratosis: Porokeratosis, HE 60x (12120) Porokeratosis, HE 60x (12117) Porokeratosis, HE 60x (12118) Porokeratosis, HE 60x (12119)

Porokeratosis: Porokeratosis, HE 60x (10794)

Porokeratosis: Porokeratosis, HE 60x (10795)

Porokeratosis: Porokeratosis, HE 60x (13907)

Porokeratosis Mibelli: Porokeratosis Mibelli, HE 20x (5400)

Porokeratosis Mibelli: Porokeratosis Mibelli, HE 20x (5409)

Porokeratotic eccrine ostial nevus, congenital lesion, where ostia of eccrine glands are bound to cornoid lamellae: Porokeratotic eccrine ostial nevus, HE 60x (6306) Porokeratotic eccrine ostial nevus, HE 60x (6315)

Porokeratosis changing into squamous cell carcinoma: Porokeratosis, squamous cell carcinoma, HE 40x (10058) Porokeratosis, squamous cell carcinoma, HE 40x (10059) Porokeratosis, squamous cell carcinoma, HE 40x (10060) Porokeratosis, squamous cell carcinoma, HE 40x (10061)

Porokeratoma or porokeratotic ostial nevus (isolated lesion): Porokeratoma or porokeratotic ostial nevus, HE 60x (13751)

Follicular porokeratosis, lamellae at ostia of hair follicles: Porokeratosis follicularis, HE 60x (13908) Porokeratosis follicularis, HE 60x (13909)

Porokeratoma: Porokeratoma, HE 60x (14393)