Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Darier's disease
Introduction

Disease characterized by keratinisation disorder.

Etiology, pathogenesis
  • monocellular keratinisation
  • acantholysis
Clinical signs
  • rare chronic familial disease
  • symetric eruption on the trunk in seborrhoeic pattern, on the face, neck, nails, palms, scalp, mouth
  • multiple closely packed warty papules
  • grey-brown, brown, brown-red colour
  • erosions, oozing, foul smell

Warty dyskeratom is regarded as an isolated form of Darier's disease.

Pictures

Darier's disease, lesions of the breast and temples: Darier's disease, Clinical picture (696)

Darier's disease: Darier's disease, Macro (3853) Darier's disease, Macro (3854) Darier's disease, Macro (3855) Darier's disease, Macro (3856)

Darier's disease, nail lesions: Darier's disease, Clinical picture (698)

Darier's disease, typical lesions of the intertriginous areas under the breasts: Darier's disease, Clinical picture (699)

Darier's disease, intertriginous areas under the breasts: Darier's disease, Clinical picture (700)

Darier's disease, widespread dissemination on the trunk with irritation: Darier's disease, Clinical picture (701)

Keratosis follicularis, back: Keratosis follicularis, Clinical picture (1063)

Darier's disease, detail of eroded papule: Darier's disease, Clinical picture (702)

Darier's disease, lesions of the back with erosions: Darier's disease, Clinical picture (703)

Darier's disease: Darier's disease, Clinical picture (5594) Darier's disease, Clinical picture (5595) Darier's disease, Clinical picture (5596)

Histology

Hyperkeratosis, dyskeratotic cells (corps ronds and grains), suprabasal acantholytic clefts.

Pictures

Darier's disease: Darier's disease, HE 5x (62) Darier's disease, HE 10x (63) Darier's disease, HE 40x (64)

Another case: Darier's disease, HE 40x (2574)

Another case: Darier's disease, HE 40x (2620)

Another case: Darier's disease, HE 20x (4449) Darier's disease, HE 40x (1246)

Another case: Darier disease, HE 60x (11002)

Another case: Darier's disease, HE 40x (5506)

Another case: Darier's disease, HE 20x (4448)

Another case: M. Darier, HE 60x (12003)

Another case: Darier disease, HE 60x (10149) Darier disease, HE 60x (10150)

Another case: Darier's disease, HE 60x (13200)

Another case: Darier's disease, HE 60x (12470)

Another case: Darier's disease, HE 60x (13928)

Another case: Darier's disease, HE 60x (14363)

Intradermal melanocytic nevi in a patient with the Darier's disease: Darier's disease and melanocytic nevus, HE 40x (3596) Darier's disease and melanocytic nevus, HE 40x (3597) Darier's disease and melanocytic nevus, HE 40x (3598)