Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Compound melanocytic nevus
Clinical signs
  • variably pigmented papule
  • size varies, from milimeters to many centimeters
  • the surface is sometimes hairy
  • different types: flat papules (esp. on the back), polypoid lesions (abdomen, lateral aspects of the trunk), firm, domed papules (face)
Histology

Melanocytic lesion with junctional part (intraepidermal nests) and dermal part (dermal nests of melanocytes). The dermal melanocytes usually mature (their size decreases downward, sometimes neuroid transformation is present). The lesion is symmetric, borders are sharp.

Nevi on palms or soles (acral nevi) can have some melanocytes scattered intraepidermally. Transcutaneous elimination of pigment is regular (columns) and lateral borders are sharp.

Compound melanocytic nevus (6337)