Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Dermal nevus
Clinical signs
  • papule, variably pigmented
  • size variable
Histology

Melanocytes in nests, strands and as single units within the dermis. Their shape is roudnish or cuboid, cytoplasm well defined, nuclei are roundish or oval, pale, chromatin is fine. Multinuclear melanocytes are sometimes found. The amount of melanin is variable.

Deepest areas of the nevus are composed of elongated melanocytes; their chromatin is fine. The amount of melanin is low or no melanin is present at all.

Neuroid transformation is sometimes present.

The amount of melanophages is variable.

Dermal nevus (10915)

Dermal nevus (10915)

Pictures

Intradermal melanocytic nevus: Melanocytic nevus, intradermal, HE 60x (13291)

Dermal nevus: Melanocytic nevus, intradermal, HE 40x (2306)

Another case: Melanocytic nevus, intradermal, HE 40x (2577)

Another case: Dermal melanocytic nevus, HE 60x (10881)

Another case: Melanocytic nevus, intradermal, HE 60x (10915)

Another case: Melanocytic nevus, intradermal, HE 40x (10940)

Another case: Melanocytic nevus, intradermal, HE 60x (12713)

Intradermal melanocytic nevus with clonal proliferation: Dermal clonal melanocytic nevus, HE 40x (10892)

Intradermal melanocytic nevus with neuroid maturation: Intradermal melanocytic nevus with neuroid maturation, HE 20x (13216)

Intradermal melanocytic nevus with neuroid maturation, polypoid: Intradermal nevus with neuroid differenciation, HE 40x (12714) Melanocytic nevus with neuroid maturation, HE 40x (12489)

Intradermal melanocytic nevus: Intradermal nevus with neuroid differenciation, HE 40x (12715)

Intradermal melanocytic nevus, papillomatous: Intradermal melanocytic nevus, papillomatous, HE 60x (12490)

Another case, with tiny osteoma: Intradermal melanocytic nevus, HE 60x (10845)

Intradermal melanocytic nevus with minimal pigment production and verrucous surface: Melanocytic nevus, intradermal, HE 20x (4294)

Intradermal melanocytic nevus with papillomatous surface: Papillomatous melanocytic nevus, HE 40x (10893)

Dermal nevus with neuroid differentiation: Melanocytic nevus, intradermal, HE 40x (2305)

Traumatized dermal melanocytic nevus: Melanocytic nevus, traumatized, HE 40x (2579)

Melanocytic nevus with fat tissue: Melanocytic nevus, intradermal, lipomatous, HE 20x (4805)

Another case of a nevus with fat (“old fatty nevus”): Melanocytic nevus, intradermal, with fat, HE 40x (5133)

Another case of a nevus with fat: Melanocytic nevus, intradermal, with fat, HE 60x (13367)

Intradermal melanocytic nevus with many multinuclear melanocytes: Melanocytic nevus, intradermal, with multinuclear melanocytes, HE 40x (12922)

Intradermal melanocytic nevus under seborrhoic keratosis: Intradermal melanocytic nevus under seborrhoic keratosis, HE 20x (13749)

Flat seborrhoic keratosis: Seborrheic keratosis, flat, HE 40x (12569)

Intradermal melanocytic nevus with teleangiectasias or combined with capillary hemangioma: Hemangioma, n. teleangiectaticus, HE 60x (10780)