Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Histiocytosis X
Introduction

Occurs in several forms (malignant Letterer-Siwe, Hand-Schüller-Christian with storing and eosinophilic granuloma). Affects various organs, including the skin.

Histology

Malignant form is characterized by dense tumorous infiltration of the epidermis, sometimes infiltrating the epidermis as well. The cells have kidney-shaped, sometimes polymorphic nuclei and eosinohilic cytoplasm. Are S100 protein and CD1a antigens positive, electron microscopy detects Bierbeck granules.