Pathology
Images
Atlas of Bone Marrow pathology
Mojmir Moulis, Josef Feit et al.
×
+ Introduction
+ Support
+ Bone Marrow Pathology
Erythroid hyperplasia
Etiology, pathogenesis
  • results from increased erythropoietin production due to chronic hypoxemia (high altitude stays, chronic lung diseases, cyanotic heart defects) or (rarely) due to erythropoietin-producing tumors (for example renal cell carcinoma)
  • or from an increased peripheral erythrocyte loss (for example hemolytic anemias)
Histology

The marrow is normo- or hypercellular with increased normoblastic erythropoiesis, which is organised in clusters. Erytropoietic precursors mature, often there is a left shift. Other hematopoietic lineages are normal.