Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Well's syndrome
Clinical signs
  • papules, plaques, sometimes vesicles
  • location: trunk, extremities
  • acute onset, lasts several weeks
  • livid, firm papules gradually heal
  • may recurr
Histology

Dense dermal perivascular and interstitial infiltrate with many eosinophils, which are partially degranulated. Alteration of collagen of variable extent, often surrounded by epithelioid cells: flame figures. The infiltrate may reach deep into the dermis, subcutis and even deeper.