Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Urticaria
Introduction

Usually transient problem characterized by dermal edema. Chronic forms do exist, sometimes together with vasculitis.

Etiology, pathogenesis
  • hypersentitive reaction to various stimuli: alergic (IgE or complement mediated: food, drugs, insects), non-allergic (physical stimuli, like cold, vibrations, pressure) or idiopathic.
Clinical signs
  • anywhere on the skin including the lips, mucosal surfaces affected as well
  • color is white, pink or red
  • lesions can be generalized, localized, circinate, annular etc.
  • angioedema: edema of the lips and mucous membranes
  • acute attacs disappear within sevetal hours
  • chronic forms recurr
  • pruritus
  • papules, wheals, edematous plaques, angioedema
Histology

Edema in upper and middle dermis, often histologically less conspicuous than clinical appearance; perivascular mixed imfiltrate containing neutrophils and/or eosinophiles.