Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Syringoma
Clinical signs
  • location: periorbital skin, neck, genital; more common in women
  • tiny, smooth nodules
  • color: skin color or pink
  • variants: linear, eruptive
  • clinically may resemble eczematous dermatitis (specimens of syringoma come under this diagnosis to pathology sometimes)

Syringoma, lower eyelid (928)

Syringomas, face (762)

Histology

The tumor consists of many tiny cellular nests and ducts, containing PAS positive material. The lining is flat or two-layered. Focal keratinisation is often present. Small cellular nests are assymmetric, of “tadpole” shape. The tumor is usually small, limited to the upper dermis.