Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Staphylococcal scalded skin syndrome
Etiology

Caused by staphylococcal exotoxin (exfoliatin).

Clinical signs
  • age: children
  • generalized erythemas, painful skin, large flaccid bullae
  • location: trunk, neck
  • mucous membranes are not involved
  • denudation of large areas after rupture of the bullae
  • good prognosis unless septicaemia develops
Histology

Large subcorneal bullae, focal subcorneal acantholysis, sparse mixed (lymphocytes, neutrophils) infiltrate.

Direct immunofluorescence is negative.