Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
×
+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Solar keratosis
Clinical signs
  • predilection areas: face (forhead, temples, nose), ears, dorsa of the hands, back
  • variants: erythematous, hypertrophic, atrophic, papulous, lichenoid, pigmented; cornu cutaneum, actinic cheilitis a conjunctivitis
  • ulcerations and bleeding should raise suspicion of malignant transition

Solar keratosis (963)

Solar keratosis (3051)

Pictures

Actinic keratosis, head; the size and hemorrhagic crust are suspicious of change into squamous carcinoma: Actinic keratosis, Clinical picture (653)

Multiple actinic keratoses: Actinic keratosis, Clinical picture (962)

Actinic keratoses: Actinic keratosis, Clinical picture (963)

Actinic keratosis: Solar keratosis, Clinical picture (3051) Solar keratosis, Clinical picture (3052)

Further examples of actinic keratosis:

Histology

Intraepidermal carcinoma, characterised by dysplastic keratinocytes (especially in lower third of the epidermis). In some cases the acantholysis is present (lower part of the epidermis). Parakeratosis, sometimes hyperkeratosis.

Several forms: atrophic, acantholytic, hyperkeratotic.

Common features are dysplastic epithelium with mitotic activity and loss of dermal polarity. The dysplastic epithelium usually spreads down into the epithelium of the hair follicles.

Later infiltrative growth and transition into low grade squamous carcinoma.

Solar keratosis (6408)