Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
×
+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Classification
Introduction

This group of diseases is usually classified according to the location and way of origin of the blisters:

Subcorneal:
in pemphigus foliaceus, staphylococcal impetigo...
Intraepidermal:
within stratum spinosum; further classification according to the way of origin:
Spongiotic:
caused by excessive spongiosis; usually some inflammatory cells are present. Examples: allergic dermatitis, dyshidrotic dermatitis
Cell ballooning:
often caused by viruses (herpes)
Acantholytic:
cellular cohesivness is lost, stratum spinosum desintegrates: pemphigus vulgaris, Darier's disease...
Subepidermal:
epidermolysis bullosa, porphyria cutanea tarda, lichen sclerosus et atrophicus, dermatitis herpetiformis Duhring and others. Subepidermal bullae appear after epidermal necrosis (vascular occlusion, phlegmone etc.).