Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Schwannoma (neurilemmoma)
Clinical signs
  • benign tumors arising in any periferal nerve
  • age: usually adults
  • well demarcated, roundish nodules; solitary or multiple
  • the tumors lie adjacent to nerves
Histology

Well demarcated proliferation of Schwann cells with elongated nuclei with roundish ends; chromatin is fine. The cells form loose fascicles with nuclei aligned in parallel arrays (Verocay bodies): structure Antoni A. Other areas of the tumor are less cellular, myxoid, edematous; aligning of nuclei is usually not conspicuous: Antoni B areas.

S100 protein is positive.

Schwannoma (2127)

Schwannoma, S100 (2128)