Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Purpura
Introduction

Small capillaries are affected in a group of diseases calledProgressive pigmented purpura of Schamberg Majjocchi, in stasis dermatitis and other diseases (gonococcal or meningococcal sepsis).

Clinical signs
  • area of predilection: lower extremities
  • skin hemorrhages: petechiae, maculae, papulae (palpable purpura), ecchymoses, suffusions
  • necroses, vasculitis
  • heals ad integrum or with residual pigmentations:
Histology

Purpura Majocchi-Schamberg is characterized by slight alteration of superficial capillaries with hemorrhage and perivascular lymphocytic infiltrate.

Purpura Schönlein-Henoch is classified as a vasculitis.

Pictures

Capillaritis of Schamberg purpura type: Purpura pigmentosa chronica, HE 20x (346)

Another case: Capillaritis, HE 20x (284) Capillaritis, HE 40x (287)

Same case, special staining, green trichrome: Capillaritis, Goldner 20x (283) Capillaritis, Goldner 40x (286)

Purpura of Schamberg: Purpura Schamberg, HE 20x (1671)

Purpura pigmentosa: Progressive pigmented purpura, early stage, HE 40x (3583)

Another case, minimal inflammation: Purpura pigmentosa chronica, HE 10x (344) Purpura pigmentosa chronica, HE 20x (343) Purpura pigmentosa chronica, HE 40x (345)

Purpura Schamberg: Progressive pigmented purpura, early stage, HE 40x (4979)

Direct immunofluorescence (FITC), antibody against the fibrin (the same case as above): Capillaritis, FITC 40x (285)

Capillaritis with admixture of neutrophils: Capillaritis with neutrophils, HE 20x (288) Capillaritis with neutrophils, HE 40x (289)

Lichen aureus, chronic purpura (HE and Perls for hemosiderin): Lichen aureus, HE 40x (4373) Lichen aureus, Prussian blue 40x (4372)

Lichen aureus, another case: Lichen aureus, HE 40x (2112)

Lichen aureus, another case: Lichen aureus, HE 20x (5113) Lichen aureus, HE 40x (2361)

Lichen aureus, another case: Lichen aureus, HE 60x (10684)

Another case of lichen aureus: Lichen aureus, HE 40x (4134) Lichen aureus, Prussian blue 40x (4133)

Another cases: Lichen aureus, HE 20x (4332) Lichen aureus, HE 20x (4333)

Lichen aureus: Lichen aureus, HE 10x (1401) Lichen aureus, HE 40x (1402) Lichen aureus, HE 40x (1403)

Lichen aureus, HE and staining for iron: Lichen aureus, HE 40x (6120) Lichen aureus, Prussian blue 40x (6119)

Lichen aureus, HE and staining for iron: Lichen aureus, HE 60x (6389) Lichen aureus, Prussian blue 60x (6388)

Lichenoid purpura Doucas and Kapetanakis: Lichenoid purpura, HE 40x (6033)