Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
B cell pseudolymphoma
Clinical signs
  • location: usually ear lobes, breasts, face, extremities and other
  • solitary nodules, infiltrated plaques, rarely multiple
  • color dark red or pink

Pseudolymphoma (804)

Pseudolymphoma (4180)

Pictures

Lymphocytoma in borreliosis: Lymphocytoma, Clinical picture (802)

Lymphocytoma, disseminated lesion of the temple: Lymphocytoma, Clinical picture (803)

Lymphocytoma of the nose: Lymphocytoma, Clinical picture (804)

Lymphocytom of the earlobe: Lymphocytoma, Clinical picture (805)

Pseudolymphoma, forhead: Pseudolymphoma, forehead, Clinical picture (4180)

Histology

Dense, often nodular infiltrate with reaction centers, reaching deep into the dermis or subcutaneous fat. The infiltrate is top heavy. No epidermotropism (grenz zone). Lymphocytes are regular.

Adnexal structures are not destroyed. Admixture of reactive inflammatory cells within the infiltrate (eosinophils, plasma cells). Dendritic cells and tingible body macrophages are present as well.

Immunophenotype and genetic features:

  • T cells (CD3+, CD43+) surround B cells (CD20+).
  • regular network of dendritic cells (CD21+) within the follicular structures.
  • polytypic expression of kappa and lambda Ig light chains

Pseudolymphoma (12933)

Pictures

Pseudolymphoma B: Pseudolymphoma, HE 2x (515) Pseudolymphoma, HE 10x (514) Pseudolymphoma, HE 20x (516) Pseudolymphoma, HE 40x (517) Pseudolymphoma, CD20 20x (518) Pseudolymphoma, CD45ro 20x (519)

Another case: Pseudolymphoma B, HE 20x (3272) Pseudolymphoma B, HE 40x (3273) Pseudolymphoma B, HE 100x (3270) Pseudolymphoma B, CD20 20x (3271) Pseudolymphoma B, CD3 20x (3504) Pseudolymphoma B, Ki67 20x (3505) Pseudolymphoma B, child 3 years, FISH 40x (3461) Pseudolymphoma B, child 3 y, FISH 40x (3465) Pseudolymphoma B, child 3 y, FISH 40x (3466) Pseudolymphoma B, child 3 y, FISH 40x (3467)

Another case: Pseudolymphoma, HE 2.5x (1642) Pseudolymphoma, HE 10x (1641) Pseudolymphoma, HE 40x (1644) Pseudolymphoma, HE 40x (1643)

Another case: Pseudolymphoma B, HE 40x (2433)

Another case: Pseudolymphoma B, HE 40x (2256)

Follicular hyperplasia: Follicular hyperplasia, HE 20x (2390) Follicular hyperplasia, HE 20x (2392)

Pseudolymphoma B: Pseudolymphoma B (PSLB), HE 40x (10282) Pseudolymphoma B (PSLB), CD20 40x (10280) Pseudolymphoma B (PSLB), CD3 40x (10281)

Pseudolymphoma B: Pseudolymphoma scroti, HE 40x (12729) Pseudolymphoma scroti, CD3 40x (12728) Pseudolymphoma scroti, CD20 40x (12726) Pseudolymphoma scroti, CD21 40x (12727) Pseudolymphoma scroti, bcl2 40x (12838) Pseudolymphoma scroti, bcl6 40x (12631)

Pseudolymphoma B: Pseudolymphoma B of the skin, follicular, HE 40x (13242) Pseudolymphoma B of the skin, follicular, HE 40x (13238)

Pseudolymphoma B: Pseudolymphoma B of the skin, follicular, HE 60x (13240)

Pseudolymphoma B: Pseudolymphoma, HE 60x (12933)

Pseudolymphoma B: Pseudolymphoma B of the skin, follicular, HE 60x (13239)

Pseudolymphoma under squamous cell carcinoma: Pseudolymphoma below squamous cell carcinoma, HE 60x (13243)

Reactive subcutaneous lymphodes: Reactive lymphnode, subcutaneous, HE 40x (12730)