Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Pityriasis rosea Gibert
Etiology, pathogenesis
  • unknown, possibly Herpes virus
  • age 10 – 35 years
Clinical signs
  • symetrical involvement of the trunk and extremities
  • pink macules and papules with central scaling and a collarette
  • generalized exanthema is preceded by a herald plaque; larger solitary lesion
  • mild pruritus
  • the dissemination is usually preceeded by a“herald patch”, a (usually) single, red, slightly elevated patch, size 2 – 5 cm
  • dull pink, scaling papules and plaques
  • trunk, neck, proximal parts of the extremities
  • lasts one or two months
Histology

Perivascular infiltrate in upper dermis (lymphocytes), slight epidermotropism. Slight spongiosis, slight acanthosis, scattered necrotic keratinocytes, focal parakeratosis, dermal hemorrhage.