Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Pellagra
Etiology

Deficiency of niacin.

Clinical signs
  • alcoholics, anorectic patients, patients treated with isoniazid
  • complex of changes (dermatitis, diarrhea, dementia)
  • location: sun exposed areas
  • erythema, sometimes vesicles; later scaling, epidermal atrophy
Histology

Upper layers of the epidermis are pale; parakeratosis; variable acanthosis; variable superficial lymphohistiocytic infiltrate; dermal fibrosis.