Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
×
+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Trichomatricoma (pilomatrixoma)
Clinical signs
  • firm, roundish, solitary subcutaneous nodule
  • location: variable, especially the upper extremities or the face
  • size: 5 – 30 mm
  • age: any age, common in children
Histology

Nodule consisting of dark, basophilic cells, often of high mitotic activity and pale, eosinophilic areas of keratin and necrotic cells with eosinophilic cytoplasm and lost nucleus (“ghost cells”).

Dystrophic calcifications and inflammatory reaction are common, sometimes ossificatinons can be found.

Trichomatricoma (10276)

Trichomatricoma (10276)