Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Lupus vulgaris
Clinical signs
  • face, acral areas
  • more frequent in women
  • nodules, infiltrated plaques, verrucosities
  • lesions covered with atrophic skin
  • slow spread
  • red-brown color
  • lupomas can be demonstrated by diascopy
  • healing with atrophic and mutilating scarrs, recurrecnes common
Histology

Epithelioid granulomas (epithelioid cells, lymphocytes, multinuclear giant cells of Langhans), plasmatic cells, sometimen neutrophils; granulation tissue and fibrosis, verrucous and pseudoepitheliomatous hyperplasia of the epidermis or atrophy. Caseous necrosis is present only sometimes, and usually not pronounced. Special stainings for mycobacteria are usually negative.