Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Leishmaniasis
Introduction

Nodular leishmaniasis contain many macrophages, epithelioid cells and plasmocytes. Leishmania donovani can be found in the cytoplasm of histiocytes.

Etiology
Pictures

Leishmania under electron microscope: Leishmania, electron microscope (6055)

Clinical signs
  • 3 forms: localized cutaneous, mucocutaneous and visceral
  • location: usually face or extremities
  • ulcerating nodules, may be several cm in size
  • crusts sometimes
  • heals after several months with scar
Pictures

Leishmaniasis, hand: Leishmaniasis, Clinical picture (782)

Leishmaniasis, detail: Leishmaniasis, Clinical picture (783)

Leishmaniasis, cheek: Leishmaniasis, cheek, Clinical picture (4178)

Further examples of leishmaniasis:

Histology

Mixed infiltration with lymphocytes, plasmocytes, pale and epithelioid macrophages, some of them containing fine granules within their cytoplasm. Microorganisms (2 µm Leishman-Donovan bodies) are found within macrophages and free in the tissue. Giemsa staining is helpful.

Pictures

Another case: Leishmaniasis, HE 1.25x (1386) Leishmaniasis, HE 10x (1385) Leishmaniasis, HE 40x (1387) Leishmaniasis, HE 63x (1389) Leishmaniasis, HE 20x (5178) Leishmaniasis, Giemsa 63x (1388)

Another case: Leishmaniasis, HE 20x (2404) Leishmaniasis, HE 40x (2405)

Another case, histology and cytology: Leishmaniasis, HE 40x (4007) Leishmaniasis, cytology, Giemsa 40x (3662) Leishmaniasis, cytology, Giemsa 40x (3663)

Another case: Leishmaniasis, HE 40x (13068) Leishmaniasis, HE 40x (13069) Leishmaniasis, Giemsa 40x (13067) Leishmaniasis, Giemsa 40x (13070)

Leishmaniasis: Leishmaniasis, HE 100x (499) Leishmaniasis, HE (296) Leishmaniasis, HE (295)

Another case: Leishmaniasis, HE 20x (5185)

Another case: Leishmaniasis, skin, HE 60x (13445)

Acute leishmaniasis and healing after several months: Leishmaniasis, Giemsa 60x (13890) Leishmaniasis, healing, HE 60x (13891)