Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Kaposiform hemangioendothelioma
Clinical signs
  • rare, aggressive vascular tumor
  • age: infants and children
  • possible complication: consumption coagulopathy (syndrome Kasabach Merritt)
  • locally aggressive, but no metastatic potential
  • location: trunk, limbs, retroperitoneum
  • skin is affected in about 75% of cases
Histology

Large tumorous masses, infiltrative, consisting of spindle cells with focal formation of slit-like lumina. Deep extension, infiltration of deep soft tissues and bone. CD31 and CD34 positive, f. VIII. positivity is variable. Areas of fibrosis or vascular differentiation may be present.

Kaposiform hemangioendothelioma (4977)

Pictures

Kaposiform hemangioendothelioma: Kaposiform hemangioendothelioma, HE 40x (4977)