Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Kaposi's sarcoma
Etiology
  • caused by infection by human herpesvirus 8 (HHV 8)
  • immunosupressions is an important co-factor (AIDS, transplantations)
Clinical signs
  • affects elder men, in younger patients it is the sign of severe immunodeficiency
  • location: often lower extremities, but other locations occur as well (including mucosal surfaces)
  • slightly infiltrated, smooth, circumscribed lesions of variable size
  • color: red, purple
  • small tumors, ulcerating
  • lymphedema may occur on lower extremities

Kaposiho sarkom (1133)

Kaposiho sarkom (5690)

Pictures

Sarcoma Kaposi, hard palate: Kaposi sarcoma, Clinical picture (774)

Sarcoma Kaposi, trunk: Kaposi sarcoma, Clinical picture (775)

Sarcoma Kaposi, elbow: Kaposi sarcoma, Clinical picture (776)

Sarcoma Kaposi, leg: Kaposi sarcoma, Clinical picture (777)

Sarcoma Kaposi : Kaposi sarcoma, Clinical picture (778)

Sarcoma Kaposi: Kaposi sarcoma, Clinical picture (1132)

Sarcoma Kaposi, heel: Kaposi sarcoma, Clinical picture (1133)

Sarcoma Kaposi, arm: Kaposi sarcoma, Clinical picture (1134)

Sarcoma Kaposi: Kaposi's sarcoma, tumor stage, Clinical picture (5688) Kaposi's sarcoma, tumor stage, Clinical picture (5689) Kaposi's sarcoma, tumor stage, Clinical picture (5690) Kaposi's sarcoma, tumor stage, Clinical picture (5691) Kaposi's sarcoma, tumor stage, Clinical picture (5692) Kaposi's sarcoma, tumor stage, Clinical picture (5693) Kaposi's sarcoma, tumor stage, Clinical picture (5694) Kaposi's sarcoma, tumor stage, Clinical picture (5695)

Further examples of sarcoma Kaposi:

Histology

3 stages of development:

Macular stage: increased cellularity within the dermis; irregular spaces between colagen fibres lined by endothelium, focally containing erythrocytes. The blood vessels, which were formerly present, remain preserved and bulge into newly formed vascular spaces.

Stage with plaques: irregular vascular dermal spaces are clearly recognisable. Endothelial cells are irregular, with some mitotic activity. Aggregates of fusiform cells with hyaline inclusions and fagocytized erythrocytes are present, as well as coins-like arrangement of erythrocytes. No thromboses can be found. Focally there are deposits of hemosiderin and hemorrhage; plasmocytes are admixtured to the infiltrate.

Tumorous stage: nodules of fusiform cells, mitotic activity, hyalin globules, erythrophagocytosis.

Early Kaposi sarkoma (4741)

Sarcoma Kaposi (1364)

Sarcoma Kaposi, plaque (2473)

Sarcoma Kaposi, nodule (13932)

Sarcoma Kaposi (4533)

Sarcoma Kaposi (12819)

Pictures

Kaposi's sarcoma, macular: Kaposi's sarcoma, macular, HE 10x (1357) Kaposi's sarcoma, macular, HE 20x (1358) Kaposi's sarcoma, macular, HE 40x (1359)

Another case of early Kaposi's sarcoma: Kaposi sarcoma, macular, early, HE 20x (4741)

Kaposi's sarcoma, patch stage: Kaposi sarcoma, patch stage, HE 60x (10785) Kaposi sarcoma, patch stage, HE 60x (10786)

Kaposi's sarcoma, patch stage: Kaposi sarcoma, patch stage, HE 60x (10787) Kaposi sarcoma, patch stage, HE 60x (10788)

Another case of Kaposi's sarcoma (leg, male, 76 years old, no AIDS): Kaposi sarcoma, macular, late, HE 40x (4027)

Kaposi's sarcoma, plaque: Kaposi's sarcoma, plaque, HE 2.5x (1363) Kaposi's sarcoma, plaque, HE 20x (1362) Kaposi's sarcoma, plaque, HE 40x (1364) Kaposi's sarcoma, plaque, HE 40x (1365) Kaposi's sarcoma, plaque, Prussian blue 10x (1360) Kaposi's sarcoma, plaque, Prussian blue 20x (1361)

Another case: Kaposi's sarcoma, plaque stage, HE 40x (2473) Kaposi's sarcoma, plaque stage, HE 100x (2471) Kaposi's sarcoma, plaque stage, CD34 40x (2472)

Kaposi's sarcoma: Kaposi's sarcoma, patch stage, HE 10x (2086) Kaposi's sarcoma, patch stage, CD34 20x (2088) Kaposi's sarcoma, patch stage, HE 40x (2087) Kaposi's sarcoma, plaque stage, HE 40x (2111)

Another case: Kaposi sarcoma, tumor stage, HE 60x (12072) Kaposi's sarcoma, plaque stage, HE 20x (4738) Kaposi's sarcoma, plaque stage, HE 20x (4740)

Another case with nodules of spindle shaped endothelial cells: Kaposi sarcoma, tumor stage, HE 40x (12819) Kaposi's sarcoma, plaque stage, HE 20x (4739)

Ulcerated Kaposi's sarcoma: Kaposi sarcoma, tumor stage, HE 40x (12820) Kaposi's sarcoma, ulcerated tumor, HE 20x (5341)

Kaposi's sarcoma, AIDS patient: Kaposi's sarcoma, plaque stage (AIDS), HE 20x (4679) Kaposi's sarcoma, plaque stage, Prussian blue 20x (4678) Kaposi's sarcoma, plaque stage (AIDS), HE 20x (4681) Kaposi's sarcoma, plaque stage (AIDS), Prussian blue 20x (4680) Sarcoma Kaposi, AIDS, HE 60x (14373)

Kaposi's sarcoma: Kaposi's sarcoma, tumorous stage, HE 20x (4519)

Kaposi's sarcoma, patch-plaque: Kaposi sarcoma, patch-plaque stage, HE 60x (12435)

Kaposiho sarcoma, nodule: Sarcoma Kaposi, nodule, HE 60x (13932)

Kaposi's sarcoma, tumorous: Kaposi sarcoma, tumor stage, HE 40x (13028)

Lymphangioma-like Kaposi's sarcoma: Kaposi sarcoma, macular, early, HE 20x (4533)