Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Hemosiderin
Introduction

Intradermal deposits of iron (hemosiderin) are usually associated with hemorrhage (purpura, stasis dermatitis), siderosis around foreign bodies. Skin pigmentation in hemochromatosis is caused by epidermal melanin, but hemosiderin is present as well.

Histology

Hemosiderin deposits within the dermis can be stained by Prussian blue staining.

Pictures

Hemosiderin: Hemosiderin, HE 10x (265)

Special stain for iron (Perls) — hemosiderin is stained blue: Hemosiderin, Prussian blue 10x (264)

Similar case in higher magnification: Hemosiderin, HE 40x (267) Hemosiderin, Prussian blue 40x (266)

Black heel, hemosiderin within the cornified layer: Black heel, HE 20x (4222)

Another case: Black heel, HE 20x (4428)

Another case: Black heel, HE 20x (4790)

Another case: Black heel, HE 20x (5085) Black heel, benzidin 20x (5084)

Another case: Black heel, HE 60x (14286)

Traumatic hematoma, nail: Nail hematoma, HE 20x (5214)

Nail hematoma, toe (clinical suspition for melanoma): Nail hematoma, HE 20x (13900)

Siderosis of the fat in a small child treated for malignancy (etiology unknown): Siderosis of the fat, after blastoma; chemotherapy, HE 20x (5414)