Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Epidermal proliferating cyst
Introduction

Rare type of epidermal cyst, where the epithelium proliferates like in proliferating trichilemal cyst. Differentiation of a carcinoma within the epidermal cyst (malignant proliferating epidermal cyst) is difficult (cellular atypia, infiltrative growth).

Prognosis is usually good.

Histology

Epidermal cyst with granular layer, filled with keratin squames, partially or completely filled by proliferating squamous epithelium with atypia.

Malignant variant has infiltrative growth, celluar atypia and high mitotic activity.

Proliferating epidermal cyst (4954)

Pictures

Proliferating epidermal cyst with focally presens granular layer, inflammed: Proliferating epidermal cyst, HE 20x (4954)