Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Epidermolytic hyperkeratosis
Etiology
  • autosomal dominantly inherited disease
Clinical signs
  • rare disease
  • affects the whole body
  • changes present at birth
  • erythema, widespread scaling
  • vesicles and bullae formed during the early course of the disease
  • the skin is dry
Pictures

Erythrodermia ichthyosiformis congenita bullosa, flexures affected: Bullous congenital ichtyosiform erythroderma, Clinical picture (764)

Erythrodermia ichthyosiformis congenita bullosa: Bullous congenital ichtyosiform erythroderma, Clinical picture (765)

Histology

Hyperkeratosis, degeneration and desintegration of the epidermis (granular degeneration, epidermolytic hyperkeratosis), perinuclear clearing, keratohyaline granules, intraepidermal vesicles, increased mitotic activity.

Epidermolytic hyperkeratosis (1342)

Pictures

Epidermolytic hyperkeratosis: Ichthyosiform erythroderma, HE 10x (585) Ichthyosiform erythroderma, HE 40x (586)

Another case: Bullous congenital ichtyosiform erythroderma, HE 10x (1342) Bullous congenital ichtyosiform erythroderma, HE 40x (1343)

Another case: Congenital (dominant) ichthyosiform erythroderma (epidermolytic hyperkeratosis), HE 20x (4251) Congenital (dominant) ichthyosiform erythroderma (epidermolytic hyperkeratosis), HE 60x (12048)

Another case: Congenital (dominant) ichthyosiform erythroderma (epidermolytic hyperkeratosis), HE 60x (12049) Congenital (dominant) ichthyosiform erythroderma (epidermolytic hyperkeratosis), HE 40x (12812)

Another case: Congenital (dominant) ichthyosiform erythroderma (epidermolytic hyperkeratosis), HE 20x (4252)

Plantar epidermolytic hyperkeratosis: Congenital (dominant) ichthyosiform erythroderma (epidermolytic hyperkeratosis), HE 40x (5116)

Erythrodermia ichthyosiformis congenita bullosa: Congenital (dominant) ichthyosiform erythroderma (epidermolytic hyperkeratosis), HE 40x (5032)