Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Eczema atopicum (dermatitis atopica)
Clinical signs
  • affected areas:
    • affected areas differ with age: toddlers — the face, scalp;
    • older children and adolescents — the elbow and knee flexures, reddening of the upper half of the body and face
    • adults — localized and generalized lesions without predilections
  • atopic habitus: cheilitis sicca, wrinkles under the eylids (Dennie-Morgan's lines), loss of lateral parts of the eyebrows (Hertoghe's sign)
  • eczematous, pruriginous, dyshidrotic lesions
  • asteatosis, hyperlinearity of hands
  • severe pruritus, scratches
  • white dermographism
  • nail changes, pitting
  • lichenification
  • allergic rhinitis, conjunctivitis, asthma
  • secondary skin infections
  • raised IgE

Atopic eczema (1006)

Pictures

Atopic eczema of the thumb and nail: Eczem dermatitis, Clinical picture (717)

Crusta lactea: combination of seborrhoeic and atopic eczema: Eczem dermatitis, Clinical picture (1005)

Eczema atopicum: erythroderma Eczem dermatitis, Clinical picture (1006)

Eczema atopicum: Eczem dermatitis, Clinical picture (1007)

Eczema atopicum, impetiginized: Eczem dermatitis, Clinical picture (1008)

Eczema atopicum, prurigo: Eczem dermatitis, Clinical picture (1009)

Eczema atopicum: Eczem dermatitis, Clinical picture (1010)

Eczema atopicum: Eczem dermatitis, Clinical picture (1011)

Eczema atopicum, excoriation, lichenification: Eczem dermatitis, Clinical picture (1012)

Eczema atopicum: Eczem dermatitis, Clinical picture (1013)

Neurodermitis, clinical picture: Prurigo, Clinical picture (1098)

Atopic dermatitis: Chronic eczem dermatitis atopic, Clinical picture (2815) Chronic eczem dermatitis atopic, Clinical picture (2816) Chronic eczem dermatitis atopic, Clinical picture (2817)

Atopic dermatitis, Dennie Morgan folds: Chronic eczem dermatitis lichenified (atopic), Macro (3742)

Atopic dermatitis, child: Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5536) Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5537) Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5538) Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5539)

Atopic dermatitis: Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5540) Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5541) Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5542) Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5543) Chronic eczem dermatitis lichenified (atopic), child, Clinical picture (5544)

Further examples of atopic dermatitis:

Histology

Acanthosis, sometimes slight spongiosis, hyperkeratosis, hypergranulosis. Slight lymphocytic infiltration, sometimes with admixture of eosinophils. Fibrosis of the papillary dermis (caused by scratching). The number of mastocytes is sometimes increased.

Chronic atopic eczema corresponds histologically to the lichen simplex chronicus (neurodermitis): chronic scratching causes hyperkeratosis, fibrosis of the papillary dermis and acanthosis and primary cause often cannot be determined.

Pictures

Atopic dermatitis: Atopic dermatitis, HE 20x (140)

Atopic eczema: Atopic eczem dermatitis, HE 20x (4233) Atopic dermatitis, HE 60x (12365)

Atopic dermatitis: Atopic dermatitis, HE 60x (6399)

Atopic dermatitis: Atopic dermatitis, HE 40x (12872)