Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Toxic contact (irritative) dermatitis, acute
Clinical signs
  • skin changes are limited to the area of contact
  • skin changes depend on the concentration of the irritant, duration of contact and individual factors
  • Acute irritant contact dermatitis:
    1. erythema
    2. vesicles
    3. madidation
    4. crusts
    5. scaling
Pictures

Dermatitis contacta irritativa, madidation, caused by hair decolourant: Dermatitis toxica, Clinical picture (713)

Further examples of toxic contact dermatitis:

Histology

In toxic reaction prevails the necrosis of the epidermis, which in typical cases affects upper epidermal layers (and sometimes follicular epithelium as well).

Pictures

Toxic contact dermatitis: Toxic contact dermatitis, HE 20x (1736)

Toxic dermatitis with superficial necrosis of the epidermis: Irritant contact dermatitis, HE 40x (4838)