Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Arteriovenous malformation
Introduction

Arteriovenous malformation (arteriovenous hemangioma) is a vascular lesion, composed of capillaries, veins and arteries.

Clinical signs
  • location: variable, can occur anywhere
  • size: from small papule to large lesions, often affecting deep soft tissues
  • age: inborn lesion, gradually developing and enlarging
  • can cause blood shutning (and hemodynamic complications)
  • x-ray arteriogram shows filling and draining blood vessels
  • malformation, trophic changes, pain, local venous hypertension, gigantism, destruction of the bone, distal ischemia
  • tinnitus in lesions located on the head
  • heart failure in large lesions
  • pulsating lesions with murmur

Arteriovenous malformation (1923)

Histology

Mixture of blood vessels separated by connective tissue and fat. The size of blood vessel lumens varies. Some may have thick wall composed of connective tissue and smooth muscle (van Gieson, smooth muscle actin), corresponding to arteries and veins. Staining for elastic tissue will show lamina elastica interna in arteioles; both arteries and veins usually have variable amount of elastic fibres within outer layers of their walls. Capillaries are often crowded and resemble capillary hemangioma closely. These areas may show proliferation with mitotic activity and sometimes resemble Kaposi's sarcoma (pseudo-Kaposi's sarcoma, but this term is used for irregular vascular proliferation caused by stasis in lower extremities as well); hemosiderin deposits may be present as well.

Arteriovenous malformation (2200)

Arteriovenous malformation (2198)