Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Alopecia areata
Introduction

Localized loss of hair.

  • Alopecia areata (one or several areas without hair);
  • alopecia totalis (whole scalp is affected);
  • alopecia universalis (whole body)
Etiology, pathogenesis
  • unknown
Clinical signs
  • alopetic areas of various size and duration, sharp demarcation, roundish
  • smooth surface, no clinical signs of inflammation, scales
  • in the margins of there are broken hairs, narowing towards the follicle (exclamation marks) — sign of activity
  • alopetic areas usually regrow
  • affects usually the scalp, but sometimes any other body hairs
  • widespread forms (alopecia universalis) are permanent
Pictures

Confluent alopetic areas; ophiasis: Alopecia areata, Clinical picture (654)

Alopecia areata: Alopecia areata, Clinical picture (655)

Alopecia areata: Alopecia areata, Macro (3702) Alopecia areata, Macro (3703) Alopecia areata, Macro (3704) Alopecia areata, Macro (3705) Alopecia areata, Macro (3706)

Alopecia maligna: generalized loss of hair, bad prognosis: Alopecia areata, Clinical picture (656)

Another case of universal alopecia, boy, 9 years old, biopsy from the scalp and forearm: Alopecia universalis (scalp), HE 40x (5492) Alopecia universalis, forearm, HE 40x (5491)

Ophiasis: Ophiasis, Clinical picture (5528)

Another case of ophiasis: Ophiasis, Clinical picture (5783)

Alopecia areata: Alopecia areata, Clinical picture (5529) Alopecia areata, Clinical picture (5530) Alopecia areata, Clinical picture (5531)

Alopecia areata: Alopecia areata, Clinical picture (5532) Alopecia areata, Clinical picture (5533)

Further examples of alopetia areata:

Histology

Deep perifollicular lymphocytic inflammation (often with scattered eosinophils), diminutive early anagen follicles closer to the epidermis.

Pictures

Alopecia areata: Alopecia areata, HE 5x (164) Alopecia areata, HE 10x (161) Alopecia areata, HE 40x (163) Alopecia areata, HE 40x (162)

Another case: Alopecia areata, HE 20x (2100) Alopecia areata, HE 40x (2101)

Another case: Alopecia areata, Clinical picture (2794) Alopecia areata, Clinical picture (2795) Alopecia areata, Clinical picture (2796)

Another case: Alopecia totalis, HE 40x (2608)

Alopecia areata: Alopecia areata, HE 60x (14359) Alopecia areata, HE 60x (14360)