Pathology
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Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
Index
Contents
Authors
ExpSys: non-tumors
ExpSys: tumors
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Atypical fibroxantoma
Clinical signs
  • tumorous nodule, size up to 2 cm
  • location: head, neck, dorsa of the hands (solar damage)
  • age: elderly people
  • locally aggresive, but capable of metastizing
  • considered to be a superficial malignant fibrous histiocytoma
Histology

Nodular tumor of spindle-shaped and pleomorphic cells, not encapsulated. Admixture of large, pleomorphic cells. Mitotic activity, ulceration and necroses are present. Variably foam cells are admixtured.

Atypical fibroxantoma (4390)

Atypical fibroxantoma (13630)

Pictures

Atypical fibroxanthoma: Atypical fibroxanthoma, AFX, HE 20x (4390)

Another case: Atypical fibroxanthoma, AFX, HE 20x (4391)

Atypical fibroxanthoma, ear: Atypical fibroxanthoma (ear), HE 2.5x (1166) Atypical fibroxanthoma, HE 10x (1164) Atypical fibroxanthoma, HE 20x (1165) Atypical fibroxanthoma, HE 40x (1167) Atypical fibroxanthoma, HE 40x (1168)

Another case: Atypical fibroxanthoma, HE 20x (1169)

Another case, ulcerating AFX (HE, CD10, AE13, MelanA): Atypical fibroxanthoma, AFX, HE 60x (13943) Atypical fibroxanthoma, AFX, CD10 20x (13941) Atypical fibroxanthoma, AFX, AE13 20x (13940) Atypical fibroxanthoma, AFX, Melan A 20x (13942)

Another case: Atypical fibroxanthoma, AFX, HE 60x (6447) Atypical fibroxanthoma, AFX, vimentin 40x (6453) Atypical fibroxanthoma, AFX, Melan A 40x (6452)

Another case: Atypical fibroxanthoma, AFX, HE 60x (13630)

Another case: Atypical fibroxanthoma, AFX, HE 60x (14030)

Another case: Atypical fibroxanthoma, AFX, HE 40x (12055)

Another case, MelanA: Atypical fibroxanthoma, AFX, Melan A 20x (13976)

Atypical fibroxanthoma, spindle cell variant: Atypical fibroxanthoma, spindle cell variant, HE 60x (10473)

Atypical fibroxanthoma: Malignant fibrous histiocytoma, HE 20x (4819)

Atypical fibroxanthoma: Atypical fibroxanthoma or malignant fibrous histiocytoma, HE 40x (12913)

Atypical fibroxanthoma: Atypical fibroxanthoma, AFX, HE 60x (13764) Atypical fibroxanthoma, AFX, AE13 20x (13762) Atypical fibroxanthoma, AFX, Melan A 20x (13763)

Atypical fibroxanthoma: Atypical fibroxanthoma, AFX, HE 60x (14254)

Atypical fibroxanthoma (superficial pleomorphic sarcoma), very high mitotic activity: Atypical fibroxanthoma, very high mitotic rate, HE 20x (14309) Atypical fibroxanthoma, very high mitotic rate, HE 60x (14313) Atypical fibroxanthoma, very high mitotic rate, HE 60x (14314) Atypical fibroxanthoma, very high mitotic rate, AE13 20x (14306) Atypical fibroxanthoma, very high mitotic rate, vimentin 20x (14312) Atypical fibroxanthoma, very high mitotic rate, Melan A 20x (14310) Atypical fibroxanthoma, very high mitotic rate, CD34 20x (14307) Atypical fibroxanthoma, very high mitotic rate, x 20x (14308) Atypical fibroxanthoma, very high mitotic rate, SMA 20x (14311)

Malignant fibrous histiocytoma, radiodermatitis: Malignant fibrous histiocytoma, HE 20x (4820)