Pathology
Images
Atlas of dermatopathology
Josef Feit, Hana Jedličková, Günter Burg, Luděk Matyska, Spasoje Radovanovic et al.
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+ Introduction
+ Literature
+ Support
+ Skin biopsy
+ Non-tumorous skin diseases
+ Skin tumors
+ Cysts of the skin and subcutis
+ Soft tissue lesions
+ Some lesions of the oral cavity
+ Dermatovenerology
+ Collection of histological slides by prof. Günter Burg
+ Collection of histological slides by prof. Werner Kempf
+ Collection of histological slides of dr. Ram Chandra Adhikari
Adenoma (angiofibroma) sebaceum Pringle
Introduction

Associated with tuberous sclerosis (familial disease, characterized by multiple small angiofibromas.

Clinical signs
  • location (skin): face (chin, around the nose), periungual, trunk
  • multiple tiny pink or skin colored papules
  • pink periungual tumors, typically of lower extremities
  • patches of type café au lait a leukodermata
  • other organs involved: CNS, eyes, bones, gums, inner organs (phacomatosis)
  • differential diagnosis: trichoepitheliomas, cylindromas, rosacea
  • transmission is autosomal dominant

Adenoma sebaceum of Pringle (651)

Histology

Fibrosis, dilated blood vessels and angiofibromas, sometimes with star shaped fibroblasts; sebaceous glands are rather atrophic. No elastic fibres are present.

Adenoma sebaceum Pringle (4953)

Pictures